RNA Details
Disease Name
primary myelofibrosis
Tissue
bone
RNA Symbol
MIR34A
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
immunophenotypic analysis; qRT-PCR; etc.
Target
NA
Pathway
NA
PubMed ID
Title
Role of miR-34a-5p in Hematopoietic Progenitor Cells Proliferation and Fate Decision: Novel Insights into the Pathogenesis of Primary Myelofibrosis
Year
2017
Function
"Collectively our data unravel the role of mir-34a-5p in hpcs fate decision and suggest that the increased expression of mir-34a-5p in pmf hpcs could be important for the skewing of megakaryopoiesis and the production of monocytes, that are key players in bm fibrosis in pmf patients."